Are you worried that breast cancer has found its way into your family? The good news is that most cases are not the cause of inherited genetic factors. Instead, breast cancer is associated with gene mutations in breast cells that acquire over a person’s lifetime.
Only a small percentage of all breast cancers cluster in families – but that doesn’t mean you are not at risk. Hereditary breast cancers tend to develop earlier in life than in non-inherited cases. If you are worried about your cancer risk, or solely just curious about your chances of carrying the gene, Privy Health can help you understand your genetic profile plays a role in prevention and treatment.
Breast cancer is the second most commonly diagnosed cancer in women. Male breast cancer represents less than one percent of all diagnoses. Awareness of risk factors and their potential implications in terms of breast cancer genesis is most important. CGX screening can not only help quantify your cancer risk, but it can potentially reduce it as a whole.
Who is at Risk?
Genetic testing for predisposition to cancer is a personal decision made for different reasons. If a personal or family history of breast cancer has you worried, you may consider testing for BRCA1 or BRCA2 gene mutations. When either of these genes become altered, the protein product that produces tumor suppressors is not created or does not function correctly – increasing your cancer risk. Hereditary cancer screening provides vital information to help those with a strong history of cancer understand their risk for developing the disease.
About five to 10 percent of breast cancers are thought to be hereditary and caused by abnormal genes passed from parent to child. However, it’s important to understand that only some people with a gene mutation will develop cancer. For example, a woman may have a 45% to 65% chance of breast cancer — but she may never develop the disease. Meanwhile, a woman with a 25% chance may develop breast cancer.
Inherited mutations in BRCA1 and BRCA1 increase the risk of female breast and ovarian cancers — but are also becoming associated with further types, such as ovarian, colorectal and prostate. If you learn that you have a family member with these linked mutations, do not panic. Privy Insight results can help prevent or detect cancer early when you or your family member has a higher chance of successful treatment.
CGX Testing in Men and Women
The average woman in the United States has about a 12% risk of developing breast cancer in her lifetime. The BRCA1 and BRCA2 genes are the most common causes of hereditary breast cancer in women. Women who inherit these gene mutations also raise their risk of developing ovarian, colon, and pancreatic cancers, along with the general population.
Cancer does not discriminate, although breast cancer is less common in men than women. Like women, men can inherit BRCA1 and BRCA2 gene mutations. Men with BRCA mutations have a 1-10% lifetime risk of developing male breast cancer. That is ten times greater than the risk for men in the general population. Additionally, those who possess an abnormal BRCA2 gene have a higher risk of developing breast, prostate, melanoma, or pancreatic cancers.
Regardless of gender, if your cancer risk is elevated, you can use your Privy Health Cancer Insight outcomes to develop a screening and treatment plan with your doctor, tailored to your unique situation.
Privy Health Cancer Insight
Your Privy Health Insight results can help you move forward with a plan of action for your particular cancer risk. We provide you with a detailed report showing the prospective susceptibility to multiple hereditary cancers. If you are concerned about your personal cancer risk, consult with Privy to gain insight. If you are diagnosed with a disease, or if a family history of a disease is revealed through testing, understanding your genetics can help you make more informed treatment decisions.