Melanoma is the most severe type of skin cancer. It only accounts for about one percent of all skin cancer types – there is four total – but it is responsible for a large quantity of skin cancer fatalities. Approximately 10 percent of patients with this condition have a family history of the disease, and genetic mutations became located in 10 to 40 percent of families with a high rate.
Sadly, more people are receiving a melanoma diagnosis than ever before. However, 90% do not carry a mutation that increases their risk. If you are worried about developing skin cancer, consider assessment through our Privy Health Cancer Insight genetic screening test. By understanding your risk for hereditary melanoma, you and your healthcare professional can make more informed health decisions before the onset, or second onset of cancer.
Genetic Testing on Melanoma Cells
People who have a primary relative – a parent, sibling, or child – with melanoma are three times more likely to develop the disease than the general population and should carefully monitor themselves. You may opt for genetic testing if you or a family member had or one more of the following:
- Two or more abnormal-looking moles called Spitz nevi
- Three or more blood relatives who have had pancreatic or melanoma cancer on one side of your family
- Three or more melanomas that have spread or embedded deep into your skin
- One or more Spitz nevi and a blood relative who has melanoma
A positive test result for melanoma can help you and your doctor monitor signs of skin cancer, which can ultimately increase the rate of interception and survival. People who carry a mutation on a gene known as CDKN2A are in greater danger of developing skin cancer, pancreatic cancer, or a tumor in the central nervous system.
Mutations in this CDKN2A gene are responsible for 20-40 percent of hereditary melanoma cases and are likely the reason for approximately 1400-2800 cases in the U.S. each year. According to research, about 40 to 50 percent out of every 100 people have this gene alteration. Taking a Privy Health CGX test solely for melanoma can provide additional insight into your overall hereditary cancer risk.
Take Precautionary Measures with Privy
When detected early, melanoma is highly treatable. The sooner the disease is exposed, the quicker you can take steps to protect yourself against associated dangers and fatalities. If you are concerned about your risk of cancer, our comprehensive testing panel analyzes over 100 genes and tumor markers, including APC, BRCA1, BRCA2, MLH1, CDKN2A, CDH1, and MSH2. Privy Health Hereditary Cancer Insight helps you understand how your genetic profile impacts your predisposition to 25 types of disease.